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KMID : 1151820210150030313
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Journal of the Korean Society of Radiology
2021 Volume.15 No. 3 p.313 ~ p.320
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Radiation Protection Effects of Schizonepeta Tenuifolia Water Extracts by Gender in SD Rats
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Lee Ji-Eun
Kim Jang-Oh
Lee Yoon-Ji
Jeon Chan-Hee
Heo Sung-Hoe
Min Byung-In
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Abstract
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This study evaluates the radiation protection effects of Schizonepeta tenuifolia water extract on white rat by gender. Schizonepeta tenuifolia contains polyphenol and flavonoid, which are typical substances that remove free radical. Thus, to determine the effectiveness of radiation protection, the Schizonepeta tenuifolia water extract was administered to Sparaqu-Dawely (SD) rat males and females for two weeks, followed by hematological analysis, analysis of changes in the length of the small intestine villi length, and SOD activity evaluation. The male rat in ST+IR group showed a slightly greater recovery of platelets than the IR group. The ST+IR group also showed a higher platelet recovery capability than the IR group. lymphocyte showed that male and female rat ST+IR groups have higher resilience than IR groups likewise platelet. After irradiation, the villi length of the male rat and female rat decreased less in ST+IR group than in the IR group, indicating that the villi length of all genders was less damaged. This result confirmed that the Schizonepeta tenuifolia water extract had a radiation protection effect.
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KEYWORD
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Schizonepeta tenuifolia, SOD, radiation protection, SD rat, gender difference
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